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Research & Evidence
NIH guidelines recommend lifestyle measures, such as dieting, physical exercise, or behavior modification therapy, for all overweight individuals who wish to lose weight.
The Role of Obesity in Cancer Survival and Recurrence - Workshop Summary
Institute of Medicine
Patrick, Megan E., PhD; Richard Miech, PhD; Lloyd Johnston, PhD; Patrick M. O’Malley, PhD; Jerald G. Bachman, PhD. "Adolescent Vaping and Nicotine Use in 2017–2018 — U.S. National Estimates." New England Journal of Medicine, December 17, 2018.
A rapid increase in the prevalence of vaping among adolescents has aroused public health concern. Adolescents who “vape” use a device such as an electronic cigarette to inhale a heated aerosol, which typically contains nicotine. In 2017, vaping was the most common use of any tobacco-like product among adolescents.1 This is a rapid rise from a near-zero prevalence of vaping in 2011.2 We assessed whether the prevalence of nicotine vaping increased among adolescents from 2017 to 2018.
Pankaj Parag Sharma, Mark Benden, Ranjana K. Mehta, Adam Pickens & Gang Han . "A quantitative evaluation of electric sit-stand desk usage: 3-month in-situ workplace study." IISE Transactions on Occupational Ergonomics and Human Factors, September 13, 2018.
Sit-stand desk interventions are deployed to reduce sedentary time and improve ergonomic adjustability in modern workplaces, with ultimate goals of improving health and productivity. Sit-stand desks, however, require workers to take an active role in changing the desk position, and usage compliance of the sit-stand function has been a challenge. This study used computer software to objectively record continuous data on electric sit-stand desk usage during computer use, to understand current desk usage behaviors in a large office environment involving ∼300 workers for 3 months. We found that workers completed roughly one desk position change per work day, and one-fourth of the workers always had the desk in a seated position (during computer use). The methods used here demonstrate a novel approach to record sit-stand desk usage continuously during active computer use.
Kuiper NM, Loomis BR, Falvey KT, Gammon DG, King BA, Wang TW, et al. "Trends in Unit Sales of Flavored and Menthol Electronic Cigarettes in the United States, 2012–2016." Centers for Disease Control and Prevention, Preventing Chronic Disease, August 23, 2018.
CDC and RTI International analyzed retail scanner data to assess national and state-specific trends in sales of flavored and menthol e-cigarettes. Findings from this analysis include:
- During 2012-2016, flavored e-cigarette sales as a percentage of all e-cigarette sales rose national from about 2% to nearly 20% in all but four states
- Menthol e-cigarette sales remained stable nationally at 35-40%
- Over half of total e-cigarette sales in 2016 were flavored or menthol products, and sales varied by product type
- Continued monitoring of the variety of flavored tobacco products available in the United States, including combustible, noncombustible, and electronic tobacco products, is critical for informing comprehensive tobacco prevention and control strategies
Wang, Teresa W., PhD; Michael A. Tynan; Cynthia Hallett, MPH; Laura Walpert, JD; Maggie Hopkins; Darryl Konter; Brian A. King, PhD. "Smoke-Free and Tobacco-Free Policies in Colleges and Universities ― United States and Territories, 2017." Morbidity and Mortality Weekly Report (MMWR), June 22, 2018.
Each year in the United States, cigarette smoking causes an estimated 480,000 deaths, including approximately 41,000 deaths from secondhand smoke exposure among nonsmoking adults. Smoke-free policies protect nonsmokers from secondhand smoke exposure, reduce the social acceptability of smoking, help in preventing youth and young adult smoking initiation, and increase smokers’ efforts to quit smoking. Given that 99% of adult cigarette smokers first start smoking before age 26 years and many smokers transition to regular, daily use during young adulthood, colleges and universities represent an important venue for protecting students, faculty, staff members, and guests from secondhand smoke exposure through tobacco control policies
Halpern, Scott D., M.D., Ph.D., Michael O. Harhay, Ph.D., Kathryn Saulsgiver, Ph.D., Christine Brophy, Andrea B. Troxel, Sc.D., and Kevin G. Volpp, M.D., Ph.D.. "A Pragmatic Trial of E-Cigarettes, Incentives, and Drugs for Smoking Cessation." New England Journal of Medicine, June 14, 2018.
BACKGROUND: Whether financial incentives, pharmacologic therapies, and electronic cigarettes (e-cigarettes) promote smoking cessation among unselected smokers is unknown.
CONCLUSIONS: In this pragmatic trial of smoking cessation, financial incentives added to free cessation aids resulted in a higher rate of sustained smoking abstinence than free cessation aids alone. Among smokers who received usual care (information and motivational text messages), the addition of free cessation aids or e-cigarettes did not provide a benefit. (Funded by the Vitality Institute; ClinicalTrials.gov number, NCT02328794.)
National Academies of Sciences, Engineering, and Medicine. "Incorporating weight management and physical activity throughout the cancer care continuum: Proceedings of a workshop." Washington, DC: The National Academies Press., 2018.
The National Cancer Policy Forum of the National Academies of Sciences, Engineering, and Medicine held a public workshop, Incorporating Weight Management and Physical Activity Throughout the Cancer Care Continuum, on February 13 and 14, 2017, in Washington, DC. The purpose of this workshop was to highlight the current evidence base, gaps in knowledge, and research needs on the associations among obesity, physical activity, weight management, and health outcomes for cancer survivors, as well as to examine the effectiveness of interventions for promoting physical activity and weight management among people living with or beyond cancer. Workshop sessions also reviewed the opportunities and challenges for providing weight management and physical activity interventions to cancer survivors. This publication summarizes the presentations and discussions from the workshop.
Marian Freedman and Michael G Burke, MD. "High-nicotine e-cigarettes lead to more smoking and vaping." Contemporary Pediatrics, February 1, 2018.
Compared with adolescents who use e-cigarettes with relatively low or no nicotine concentrations, those who use e-cigarettes with higher nicotine concentrations are more likely to progress to more frequent and intense combustible cigarette smoking and vaping.
Hackshaw, Allan; Joan K. Morris; Sadie Boniface; Jin-Ling Tang, Dušan Milenković,. "Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports." The BMJ, January 24, 2018.
Around one billion adults worldwide smoke,1 with high prevalence in developing countries, where 49% of men and 11% of women use tobacco.2 Although the prevalence of current smokers has decreased over time in several countries, the global absolute number of smokers has increased owing to population growth.3 Policies have successfully encouraged people to quit, using aids such as nicotine replacement therapy and electronic cigarettes (e-cigarettes).4
National Academies of Sciences, Engineering, and Medicine. "Public Health Consequences of E-Cigarettes." Washington, DC: The National Academies Press, 2018.
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes.
Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
Ahmed Jamal, MBBS; Elyse Phillips, MPH; Andrea S. Gentzke, PhD; David M. Homa, PhD; Stephen D. Babb, MPH; Brian A. King, PhD; Linda J. Neff, PhD. "Current Cigarette Smoking Among Adults — United States, 2016." CDC Morbidity and Mortality Weekly Report, January 19, 2018.
The U.S. Surgeon General has concluded that the burden of death and disease from tobacco use in the United States is overwhelmingly caused by cigarettes and other combusted tobacco products. Proven population-based interventions, including tobacco price increases, comprehensive smoke-free laws, anti-tobacco mass media campaigns, and barrier-free access to tobacco cessation counseling and medications, are critical to reduce cigarette smoking and smoking-related disease and death among U.S. adults, particularly among subpopulations with the highest prevalences.
"Cancer Facts & Figures 2018." American Cancer Society, January 2018.
Estimated numbers of new cancer cases for 2018, excluding basal cell and squamous cell skin cancers and in situ carcinomas except urinary bladder. Estimates are not available for Puerto Rico.
Note: State estimates are offered as a rough guide and should be interpreted with caution. State estimates may not add to US total due to rounding.
Siegel, Rebecca L., MPH; Kimbertly D. Miller, MPH; Ahmedin Jemal, DVM, PhD. "Cancer Statistics, 2018." Wiley Online Library, January 4, 2018.
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States and compiles the most recent data on cancer incidence, mortality, and survival.
Cancer is a major public health problem worldwide and is the second leading cause of death in the United States. In this article, we provide the estimated numbers of new cancer cases and deaths in 2018 in the United States nationally and for each state, as well as a comprehensive overview of cancer occurrence based on the most current population‐based data for cancer incidence through 2014 and for mortality through 2015. We also estimate the total number of deaths averted as a result of the continual decline in cancer death rates since the early 1990s and quantify the black‐white disparity in cancer mortality by state and age based on the actual number of reported cancer deaths in 2015.
Aiuppa, Laura; Maria Hewitt; Sharyl J. Nass. "Long-Term Survivorship Care After Cancer Treatment." The National Academies of Sciences, 2018.
The 2006 Institute of Medicine (IOM) consensus study report From Cancer Patient to Cancer Survivor: Lost in Transition made recommendations to improve the quality of care that cancer survivors receive, in recognition that cancer survivors are at risk for significant physical, psychosocial, and financial repercussions from cancer and its treatment (IOM and NRC, 2006). Since then, efforts to recognize and address the unique needs of cancer survivors have increased, including an emphasis on improving the evidence base for cancer survivorship care and identifying best practices in the delivery of high-quality cancer survivorship care.
Farhad Islami, MD, PhD; Ann Goding Sauer, MSPH; Kimberly D. Miller, MPH; Rebecca L. Siegel, MPH; Stacey A. Fedewa, PhD, MPH; Eric J. Jacobs, PhD; Marjorie L. McCullough, ScD, RD; Alpa V. Patel, PhD; Jiemin Ma, PhD, MHS; Isabelle Soerjomataram, MD, PhD, MS. "Proportion and Number of Cancer Cases and Deaths Attributable to Potentially Modifiable Risk Factors in the United States." CA: A Cancer Journal for Clinicians, November 21, 2017.
Contemporary information on the fraction of cancers that potentially could be prevented is useful for priority setting in cancer prevention and control. Herein, the authors estimate the proportion and number of invasive cancer cases and deaths, overall (excluding nonmelanoma skin cancers) and for 26 cancer types, in adults aged 30 years and older in the United States in 2014, that were attributable to major, potentially modifiable exposures (cigarette smoking; secondhand smoke; excess body weight; alcohol intake; consumption of red and processed meat; low consumption of fruits/vegetables, dietary fiber, and dietary calcium; physical inactivity; ultraviolet radiation; and 6 cancer-associated infections).
Elyse Phillips, MPH; Teresa W. Wang, PhD; Corinne G. Husten, MD; Catherine G. Corey, MSPH; Benjamin J. Apelberg, PhD; Ahmed Jamal, MBBS; David M. Homa, PhD; Brian A. King, PhD . "Tobacco Product Use Among Adults — United States, 2015." Centers for Disease Control and Prevention, November 10, 2017.
In 2015, approximately one in five U.S. adults (48.7 million) currently used any tobacco product, with most using combustible tobacco products. Any tobacco product use was significantly higher among males; adults aged <65 years; non-Hispanic AI/AN, whites, blacks, and persons of multiple races; persons living in the Midwest; persons with a GED; persons with annual household income <$35,000; persons who were single/never married/not living with a partner or divorced/separated/widowed; persons who were uninsured or insured through Medicaid; persons with a disability; and persons who identified as LGB. Adults with serious psychological distress had the highest prevalence of any tobacco product use of any subpopulation.