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Gold Standard Articles of Interest for Cancer Clinical Trials
Bassett, Mike. "How to get more men in breast cancer trials?." MedPage Today, October 8, 2019.
The FDA recently drafted new recommendations encouraging the inclusion of more men in breast cancer clinical trials.
The industry draft guidance urges that eligibility for breast cancer drugs should include both men and women, and that there should be a scientific rationale included in a trial protocol when men are excluded from trials.
"Making Cancer Clinical Trials Available to More Patients." NCI Cancer Currents Blog, March 7, 2019.
With so many new and promising cancer treatments being developed, the need for clinical trials to efficiently and effectively test them has never been greater.
Maximizing the number of patients who are eligible for clinical trials, while still maintaining an appropriate level of safety, is a top priority for NCI leadership, given the challenges of enrolling enough patients in clinical trials. Eligibility criteria—the requirements that must be met before a person can enroll in a trial—have not kept pace with the modernization of clinical trials. Restrictive criteria have not only been a significant hurdle for many patients who have wanted to participate in trials, but they have also limited the generalizability of study findings.
Pirschel, Chris and Sheila Prindiville, MD. "How Do You Find Clinical Trials Through the NCI’s Advanced Clinical Trials Search?." ONS Voice, September 5, 2017.
As part of the National Cancer Moonshot Initiative and in collaboration with the Presidential Innovation Fellows, the National Cancer Institute (NCI) developed and launched a new website in 2016. It provides user-friendly access to the repository of abstracts of cancer clinical trials that NCI supported.